What is the first event in the progression that leads to cystitis?

The initial event in the progression leading to cystitis is when bacteria enter the lower urinary tract. This entry can occur through various routes, such as ascending from the urethra or through the bloodstream. Once bacteria gain access, they can begin to colonize the bladder, which sets off subsequent steps in the inflammatory process.

Following this initial bacterial entry, the next phases may include adherence to the bladder wall and triggering an inflammatory response. As bacteria multiply and further colonize the area, it can lead to the characteristic symptoms of cystitis. The sequence is vital in understanding the pathophysiology of urinary tract infections and the resultant inflammation associated with cystitis.